Scientists at the Science and Technology Facilities Council (STFC) Rutherford Appleton Laboratory have developed an effective laser-based method for the characterization of the bulk chemical content of pharmaceutical capsules–without opening the capsules.
In close collaboration with teams from pharmaceutical company Pfizer, the researchers in STFC’s Lasers for Science Facility succeeded in quantifying the presence of the active pharmaceutical ingredient in production-line-relevant capsules to a relative error of 1%. Other established non-invasive methods were unable to reach the same level of accuracy with the same sample.
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